Overview
SCIENTIFIC SCORE
Moderately Effective
Based on 2 Researches
8.5
USERS' SCORE
Good
Based on 2 Reviews
8.2
Supplement Facts
Serving Size: 1 Veg Capsule
Amount Per Serving
%DV
Inositol
500 mg
**
Top Medical Research Studies
9
We explored the role of the sodium/myo-inositol co-transporter SLC5A3 in non-small cell lung cancer (NSCLC). Our research aimed to uncover how inositol impacts cancer cell growth and survival.
Through our analysis, we discovered that SLC5A3 levels were significantly higher in NSCLC tissues than in normal lung tissues. When we reduced SLC5A3 using specific techniques, we observed a notable decrease in cell growth, migration, and an increase in cell death. This suggests that SLC5A3 plays a pivotal role in maintaining cancer cell viability.
Furthermore, we found that adding myo-inositol or activating a related protein pathway helped reverse the effects seen with SLC5A3 depletion. In animal models, we noted that directly targeting SLC5A3 reduced tumor growth significantly, reinforcing the idea that it is a critical factor in NSCLC progression.
Overall, our findings highlight that SLC5A3 promotes cancer cell growth potentially by enhancing myo-inositol levels and activating specific signaling pathways. This offers new insights into potential treatment strategies targeting SLC5A3 for lung cancer patients.
Through our analysis, we discovered that SLC5A3 levels were significantly higher in NSCLC tissues than in normal lung tissues. When we reduced SLC5A3 using specific techniques, we observed a notable decrease in cell growth, migration, and an increase in cell death. This suggests that SLC5A3 plays a pivotal role in maintaining cancer cell viability.
Furthermore, we found that adding myo-inositol or activating a related protein pathway helped reverse the effects seen with SLC5A3 depletion. In animal models, we noted that directly targeting SLC5A3 reduced tumor growth significantly, reinforcing the idea that it is a critical factor in NSCLC progression.
Overall, our findings highlight that SLC5A3 promotes cancer cell growth potentially by enhancing myo-inositol levels and activating specific signaling pathways. This offers new insights into potential treatment strategies targeting SLC5A3 for lung cancer patients.
8
In our exploration of lung cancer treatments, we investigated how myo-inositol (MI) works alongside other agents to combat lung tumors. We treated A/J mice with a tobacco smoke carcinogen and followed up with various combinations of MI, iloprost (IL), and rapamycin for 17 weeks. Our analysis focused on the number and size of induced lung tumors.
The results were promising! We found that MI alone, along with its combinations with IL and rapamycin, significantly decreased the number of lung tumors. Particularly, the combination of MI with IL or rapamycin prevented the development of larger tumors, showing a strong 79% and 67% reduction in tumor multiplicity, respectively.
One striking finding of our study was the effects on immune response. Those treated with MI plus IL or rapamycin experienced increased infiltration of key immune cells into the tumors and a reduction in the expression of an immune checkpoint protein known as PD-L1. All treatment groups, aside from those receiving IL alone, also showed greater rates of cell death and reduced cell proliferation.
Through this research, we observed that combining IL or rapamycin with MI improved its effectiveness in preventing lung tumor formation and growth more than MI alone. This suggests that these combinations could be beneficial in lung cancer chemoprevention strategies.
The results were promising! We found that MI alone, along with its combinations with IL and rapamycin, significantly decreased the number of lung tumors. Particularly, the combination of MI with IL or rapamycin prevented the development of larger tumors, showing a strong 79% and 67% reduction in tumor multiplicity, respectively.
One striking finding of our study was the effects on immune response. Those treated with MI plus IL or rapamycin experienced increased infiltration of key immune cells into the tumors and a reduction in the expression of an immune checkpoint protein known as PD-L1. All treatment groups, aside from those receiving IL alone, also showed greater rates of cell death and reduced cell proliferation.
Through this research, we observed that combining IL or rapamycin with MI improved its effectiveness in preventing lung tumor formation and growth more than MI alone. This suggests that these combinations could be beneficial in lung cancer chemoprevention strategies.
Most Useful Reviews
6
Normalises female organs
6 people found this helpful
I came across numerous positive reviews about inositol. Although I had no prior knowledge of it, I bought it to assist with my polycystic disease symptoms. However, its benefits are much broader! It alleviates symptoms related to polycystic ovaries, reduces the risk of heart attacks, strokes, hypertension, and cancer, blocks panic attacks, and stabilises blood sugar in type 2 diabetes. It also enhances hair strength and growth. I recently started using it, and after three weeks, I noticed changes in my hormonal balance. Inositol is working; I also purchased folic acid for better efficacy.
7.5
Inhibits cancer growth
Multifunctional inositol is known as vitamin B8, and for optimal benefits, it should be combined with B vitamins and vitamin E. It helps remove bad fats from the liver, lowers cholesterol, promotes nerve cell repair, alleviates anxiety, provides a sedative effect, and inhibits cancer cell growth in the body.
Medical Researches
SCIENTIFIC SCORE
Moderately Effective
Based on 2 Researches
8.5
- All Researches
9
We explored the role of the sodium/myo-inositol co-transporter SLC5A3 in non-small cell lung cancer (NSCLC). Our research aimed to uncover how inositol impacts cancer cell growth and survival.
Through our analysis, we discovered that SLC5A3 levels were significantly higher in NSCLC tissues than in normal lung tissues. When we reduced SLC5A3 using specific techniques, we observed a notable decrease in cell growth, migration, and an increase in cell death. This suggests that SLC5A3 plays a pivotal role in maintaining cancer cell viability.
Furthermore, we found that adding myo-inositol or activating a related protein pathway helped reverse the effects seen with SLC5A3 depletion. In animal models, we noted that directly targeting SLC5A3 reduced tumor growth significantly, reinforcing the idea that it is a critical factor in NSCLC progression.
Overall, our findings highlight that SLC5A3 promotes cancer cell growth potentially by enhancing myo-inositol levels and activating specific signaling pathways. This offers new insights into potential treatment strategies targeting SLC5A3 for lung cancer patients.
Through our analysis, we discovered that SLC5A3 levels were significantly higher in NSCLC tissues than in normal lung tissues. When we reduced SLC5A3 using specific techniques, we observed a notable decrease in cell growth, migration, and an increase in cell death. This suggests that SLC5A3 plays a pivotal role in maintaining cancer cell viability.
Furthermore, we found that adding myo-inositol or activating a related protein pathway helped reverse the effects seen with SLC5A3 depletion. In animal models, we noted that directly targeting SLC5A3 reduced tumor growth significantly, reinforcing the idea that it is a critical factor in NSCLC progression.
Overall, our findings highlight that SLC5A3 promotes cancer cell growth potentially by enhancing myo-inositol levels and activating specific signaling pathways. This offers new insights into potential treatment strategies targeting SLC5A3 for lung cancer patients.
8
In our exploration of lung cancer treatments, we investigated how myo-inositol (MI) works alongside other agents to combat lung tumors. We treated A/J mice with a tobacco smoke carcinogen and followed up with various combinations of MI, iloprost (IL), and rapamycin for 17 weeks. Our analysis focused on the number and size of induced lung tumors.
The results were promising! We found that MI alone, along with its combinations with IL and rapamycin, significantly decreased the number of lung tumors. Particularly, the combination of MI with IL or rapamycin prevented the development of larger tumors, showing a strong 79% and 67% reduction in tumor multiplicity, respectively.
One striking finding of our study was the effects on immune response. Those treated with MI plus IL or rapamycin experienced increased infiltration of key immune cells into the tumors and a reduction in the expression of an immune checkpoint protein known as PD-L1. All treatment groups, aside from those receiving IL alone, also showed greater rates of cell death and reduced cell proliferation.
Through this research, we observed that combining IL or rapamycin with MI improved its effectiveness in preventing lung tumor formation and growth more than MI alone. This suggests that these combinations could be beneficial in lung cancer chemoprevention strategies.
The results were promising! We found that MI alone, along with its combinations with IL and rapamycin, significantly decreased the number of lung tumors. Particularly, the combination of MI with IL or rapamycin prevented the development of larger tumors, showing a strong 79% and 67% reduction in tumor multiplicity, respectively.
One striking finding of our study was the effects on immune response. Those treated with MI plus IL or rapamycin experienced increased infiltration of key immune cells into the tumors and a reduction in the expression of an immune checkpoint protein known as PD-L1. All treatment groups, aside from those receiving IL alone, also showed greater rates of cell death and reduced cell proliferation.
Through this research, we observed that combining IL or rapamycin with MI improved its effectiveness in preventing lung tumor formation and growth more than MI alone. This suggests that these combinations could be beneficial in lung cancer chemoprevention strategies.
User Reviews
USERS' SCORE
Good
Based on 2 Reviews
8.2
- All Reviews
- Positive Reviews
- Negative Reviews
6
Normalises female organs
6 people found this helpful
I came across numerous positive reviews about inositol. Although I had no prior knowledge of it, I bought it to assist with my polycystic disease symptoms. However, its benefits are much broader! It alleviates symptoms related to polycystic ovaries, reduces the risk of heart attacks, strokes, hypertension, and cancer, blocks panic attacks, and stabilises blood sugar in type 2 diabetes. It also enhances hair strength and growth. I recently started using it, and after three weeks, I noticed changes in my hormonal balance. Inositol is working; I also purchased folic acid for better efficacy.
7.5
Inhibits cancer growth
Multifunctional inositol is known as vitamin B8, and for optimal benefits, it should be combined with B vitamins and vitamin E. It helps remove bad fats from the liver, lowers cholesterol, promotes nerve cell repair, alleviates anxiety, provides a sedative effect, and inhibits cancer cell growth in the body.
Frequently Asked Questions
No FAQs are available for this product and symptom.
References
- Cui Z, Mu C, Wu Z, Pan S, Cheng Z, et al. The sodium/myo-inositol co-transporter SLC5A3 promotes non-small cell lung cancer cell growth. Cell Death Dis. 2022;13:569. 10.1038/s41419-022-05017-y
- Kassie F, Bagherpoor AJ, Kovacs K, Seelig D. Combinatory lung tumor inhibition by myo-inositol and iloprost/rapamycin: association with immunomodulation. Carcinogenesis. 2022;43:547. 10.1093/carcin/bgac019
